{"id":3242322,"date":"2024-07-30T10:43:14","date_gmt":"2024-07-30T14:43:14","guid":{"rendered":"https:\/\/www.futurity.org\/?p=3242322"},"modified":"2024-07-30T10:43:14","modified_gmt":"2024-07-30T14:43:14","slug":"pregnancy-stress-toddler-hair-cortisol-3242322","status":"publish","type":"post","link":"https:\/\/www.futurity.org\/pregnancy-stress-toddler-hair-cortisol-3242322\/","title":{"rendered":"High stress in pregnancy may show up in toddler hair"},"content":{"rendered":"
Researchers have discovered a connection between toddler hair cortisol levels\u2014a long-term stress biomarker\u2014and maternal prenatal depression.<\/p>\n
The findings in the American Journal of Human Biology<\/em><\/a> suggest that a child’s long-term stress physiology\u2014or how the body responds to stress\u2014may be influenced by conditions experienced in utero, according to study coauthor Theresa Gildner, an assistant professor of biological anthropology at Washington University in St. Louis.<\/p>\n The findings also highlight the potential for hair cortisol\u2014a minimally invasive and easy-to-collect measure\u2014to assess infant and toddler cortisol activity.<\/p>\n “Hair cortisol tests are less invasive than blood tests, the standard cortisol measurement technique, and more useful than saliva tests, which only reflect short-term changes in cortisol. With 1 centimeter of hair corresponding to roughly one month of cortisol incorporation, hair cortisol tests can quantify cumulative cortisol exposure over extended periods of time,” Gildner says.<\/p>\n According to Gildner, the study was primarily conducted for research purposes, but it also has potential clinical applications.<\/p>\n “By understanding the long-term effects of maternal stress<\/a> on her offspring and when these effects are especially pronounced during pregnancy, we can better determine when interventions to support parents and reduce stress are most needed, as well as the potential long-term benefits of investing in these kinds of interventions to support both maternal and infant well-being,” Gildner explains.<\/p>\n The hypothalamic pituitary adrenal (HPA)-axis is the body’s system for managing stress. When the body encounters stress, the HPA-axis releases a steroid hormone called cortisol. Cortisol levels naturally fluctuate throughout the day and in response to stress, but generally come back down once the threat passes.<\/p>\n Chronic stress, however, can disrupt the HPA-axis activity, causing cortisol levels to remain elevated. This can lead to serious health problems, including metabolic disease, immune system dysfunction, increased inflammation, cancer, and mental health conditions.<\/p>\n During pregnancy, cortisol readily crosses the placenta. When a pregnant person’s cortisol level remains high, it can also harm the fetus and affect development, including fetal growth rate.<\/p>\n “Changes in offspring cortisol levels could potentially be beneficial, possibly leading toward accelerated growth and development in response to early adversity. Basically, the baby is receiving signals in utero from mom that the outside world is stressful, and their growth patterns might adjust in response,” Gildner says.<\/p>\n “However, these changes might also have negative costs for the child, including lower birth weight and issues later in life, such as increased behavioral problems and elevated risk of developing cortisol-associated health conditions, such as depression, anxiety, digestive problems, and weight gain.”<\/p>\n